Not filling comfortable with WASD + QEZC in a game that is supposed to be controlled with keyboard feels awkward to me. In other words, it seems that the people who tried your game just want to complicate the whole thing when the solution is already there. Not even mouse control can be as efficient as keyboard to a control a character in a roguelike game. A perfect interface for a roguelike would be having 8 direction and mouse to operate the whole interface, including selecting targets and to get general information from every tile or foe within the character's sight range. Your friends need simply to adapt to circumstances, the same way they would need to adapt to a gaming console as there is no WASD + Mouse (vanilla setting).
In your case, whatever the solution I can think off, it just ends up adding more effort to it. I would simply add WASD + QEZC control as well as mouse support. Some game's are meant to be played in a particular way for comfort reasons. FPS use WASD + Mouse, RTS mouse only (with some UI key shortcuts), flight simulators use joystick / HOTAS (and a whole shit of key combinations) and roguelikes 8 direction key movement + mouse is advised. Trying to change these controlling mechanics is begging for masochism.
You can in fact operate any game using just 2 keys. One key to open an option screen and then pressing it again over and over to cycle through all the options the game has and finally another key to select the desired option. Heck, you could in fact operate Windows this way but I really doubt it would be a comfortable way of handling it. So yeah, you can easily have 4 keys doing the job of 8 keys but the question is, how good will it be in the end?
So in other words, if someone else asks you if they can have WASD to play your game, simply say: "No! These are they keys you need to use to play it, get used to it and you will thank me later." It is hard to believe that someone who feels already uncomfortable with the 8 direction key mapping will actually enjoy a roguelike.