I walked into this with 0 XP in roguelikes. However, I found it quite easy to pick up, beating the tutorial on my second try after accidentally running into the boss the first time through.
Attempting the Postgraduate achievement (I really wanted to play as a unicorn) definitely gave me a feel for how to find the most effective path by the time I could use a unicorn wizard, which helped me through the normal adventure.
The item system is nice, and the random set of items for purchasing at any time is interesting most of the time, though I find it can be a bit frustrating in the tutorial, as it adds an element of luck into the careful planning needed for defeating the boss without taking the element.
(Also enjoyed the special items for getting the Postgrad achievement)
I love the sense of humor you've given the game. It doesn't take precedence over other, more important things, but it works alongside them, and makes for a fun, lighthearted tone.