Completely disagree. You can always avoid all attacks and beat the game with no equipment other than what you started with. It just comes down to skill (because this is real-time and not a turn-based game).
You are right, I guess I overlooked that skill aspect of the game because it doesn't interest me. I am about as good as I'll get (average) at dodging/shooting reflexes with the isaac controls. I am more interested in skill of making decisions/choices rather than skill of aiming/dodging/reflexes.
There are strategic decisions/choices in isaac: my favorite is deciding whether to sacrifice hearts to enter a pact, and my second favorite is how many hearts to sacrifice at the blood machine in the hope of getting a blood bag.
Well, the patching is ongoing from much wackiness the new DLC added and problems with drops and such, but in general while luck is a large factor it is not the only one at play.
I agree it's not all down to luck, but a significant part of it is for me. At some point I realized that all my wins were when I had a great set of items which was largely due to the RNG. So conversely most of my losses are because of the RNG rather than a mistake I made, which is the problem.
Don't get me wrong it's one of the best games I've played but the replay lifetime of the game for me is significantly shorter because i don't find enough strategy choices. I think things would be significantly improved if in each item room or boss room there were 3 randomly dropped items and you had to chose 1, like how the pact room works. And make the shop contain more powerful items (I think that was one of the updates in the DLC? I might have to get the DLC).