Yes, I think Python has become a liability to use these days. The biggest problems I've had are getting python games to work. Mind you, some of the Python games work absolutely fine, so I imagine it's the devs that are partly to blame.
I got Stygia running, Perdurabo, and I know others have too. My own mini-review of it: "Whilst this doesn’t break new boundaries it is a solid enough roguelike, with a decent interface, no terrible bugs, and it seems reasonably balanced. Equipment items have a nice variety to them, though enemies are mostly uninteresting. The heat mechanic could do with expanding upon, but overall it’s a good game."